You can also configure Windows to automatically turn off the touchpad when you connect an external mouse to your computer via the good old mouse settings in the Control Panel. Disable Touchpad on External Mouse via Control Panel Of course, when you disconnect the external mouse, the touchpad will be enabled automatically. From now on, whenever you connect an external mouse, Windows automatically disables the touchpad.
All you have to do is select a single checkbox, and Windows 10 will turn off the touchpad on an external mouse connection. The settings app has proper options to configure Windows 10 to disable the touchpad if an external mouse is plugged in. Note: If your laptop doesn’t support a precision touchpad, then this method won’t work.
Disable Touchpad on External Mouse via Settings App